Structure–Activity Relationships Among the Nitrogen Containing Bisphosphonates in Clinical Use and Other Analogues: Time-Dependent Inhibition of Human Farnesyl Pyrophosphate Synthase-Reference-Cited by-同舟云学术

Structure–Activity Relationships Among the Nitrogen Containing Bisphosphonates in Clinical Use and Other Analogues: Time-Dependent Inhibition of Human Farnesyl Pyrophosphate Synthase

Published:2008-03-08 Issue:7 Volume:51 Page:2187-2195
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Dunford James E.¹,Kwaasi Aaron A.¹,Rogers Michael J.¹,Barnett Bobby L.¹,Ebetino Frank H.¹,Russell R. Graham G.¹,Oppermann Udo¹,Kavanagh Kathryn L.¹

Affiliation:

1. Structural Genomics Consortium, The Botnar Research Centre, University of Oxford, Oxford OX3 7LD, United Kingdom, Nuffield Department of Orthopaedic Surgery, The Botnar Research Centre, University of Oxford, Institute of Musculoskeletal Sciences, Nuffield Orthopaedic Centre, Headington, Oxford OX3 7LD, United Kingdom, Bone and Musculoskeletal Research Programme, Institute of Medical Sciences, University of Aberdeen, Aberdeen AB25 2ZD, United Kingdom, Chemistry Department, University of Cincinnati,...

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm7015733

Reference32 articles.

1. Long-Term Control of Bone Turnover in Paget's Disease With Zoledronic Acid and Risedronate

2. Bisphosphonates in breast cancer

3. Clinical evaluation of novel bisphosphonate dosing regimens in osteoporosis: The role of comparative studies and implications for future studies

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