Synthesis and Evaluation of N-Methyl and S-Methyl 11C-Labeled 6-Methylthio-2-(4′-N,N-dimethylamino)phenylimidazo[1,2-a]pyridines as Radioligands for Imaging β-Amyloid Plaques in Alzheimer’s Disease-Reference-Cited by-同舟云学术

Synthesis and Evaluation of N-Methyl and S-Methyl 11C-Labeled 6-Methylthio-2-(4′-N,N-dimethylamino)phenylimidazo[1,2-a]pyridines as Radioligands for Imaging β-Amyloid Plaques in Alzheimer’s Disease

Published:2007-12-14 Issue:1 Volume:51 Page:148-158
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Cai Lisheng¹,Liow Jeih-San¹,Zoghbi Sami S.¹,Cuevas Jessica¹,Baetas Cesar¹,Hong Jinsoo¹,Shetty H. Umesha¹,Seneca Nicholas M.¹,Brown Amira K.¹,Gladding Robert¹,Temme Sebastian S.¹,Herman Mary M.¹,Innis Robert B.¹,Pike Victor W.¹

Affiliation:

1. Molecular Imaging Branch and Clinical Brain Disorders Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm700970s

Reference42 articles.

1. Alzheimer's Disease: Genes, Proteins, and Therapy

2. Alzheimer Disease: Mechanistic Understanding Predicts Novel Therapies

3. The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics

4. Alzheimer's Disease

5. Pathways towards and away from Alzheimer's disease

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