Design of a Paclitaxel Prodrug Conjugate for Active Targeting of an Enzyme Upregulated in Breast Cancer Cells

Author:

Satsangi Arpan12,Roy Sudipa S.3,Satsangi Rajiv K.4,Vadlamudi Ratna K.3,Ong Joo L.2

Affiliation:

1. Joint Graduate Program in Biomedical Engineering, University of Texas at San Antonio and the University of Texas Health Science Center at San Antonio, San Antonio, Texas 78249, United States

2. Department of Biomedical Engineering, University of Texas at San Antonio, San Antonio, Texas 78249, United States

3. Department of Obstetrics and Gynecology, University of Texas Health Science Center at San Antonio San Antonio, Texas78229, United States

4. RANN Research Corporation, San Antonio, Texas 78250, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Reference65 articles.

1. American Cancer Society. Cancer Facts and Figures 2013. http://www.cancer.org/research/cancerfactsstatistics/cancerfactsfigures2013/index(accessed May 20, 2013) .

2. National Cancer Institute. Common Cancers Type.http://www.cancer.gov/cancertopics/types/commoncancers(accessed May 20, 2013) .

3. Taxanes Alone or in Combination With Anthracyclines As First-Line Therapy of Patients With Metastatic Breast Cancer

4. Weekly Paclitaxel in the Adjuvant Treatment of Breast Cancer

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