Bioinorganic Chemistry of Parkinson’s Disease: Structural Determinants for the Copper-Mediated Amyloid Formation of Alpha-Synuclein

Author:

Binolfi Andrés1,Rodriguez Esaú E.2,Valensin Daniela3,D’Amelio Nicola4,Ippoliti Emiliano5,Obal Gonzalo6,Duran Rosario6,Magistrato Alessandra5,Pritsch Otto6,Zweckstetter Markus78,Valensin Gianni3,Carloni Paolo5,Quintanar Liliana2,Griesinger Christian7,Fernández Claudio O.17

Affiliation:

1. Instituto de Biología Molecular y Celular de Rosario, Consejo Nacional de Investigaciones Científicas y Técnicas, Universidad Nacional de Rosario, Suipacha 531, S2002LRK, Rosario, Argentina

2. Departamento de Química, Centro de Investigación y de Estudios Avanzados (Cinvestav), Av. Instituto Politécnico Nacional 2508, 07360, D.F., México

3. Dipartamento di Chimica, Universitá degli studi di Siena, Via Aldo Moro, 53100, Siena, Italy

4. Bracco Imaging-CRB Trieste, Area Science Park, Edificio Q, S. S., 14 Km, 163.5, 34149 Basovizza Trieste, Italy

5. CNR-IOM-Democritos National Simulation Center and International School for Advanced Studies (SISSA/ISAS), via Beirut 2-4, I-34014 Trieste, Italy

6. Institut Pasteur de Montevideo, Mataojo 2020, 11400 Montevideo, Uruguay

7. Department of NMR−based Structural Biology, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, D-37077 Göttingen, Germany

8. DFG Research Center for the Molecular Physiology of the Brain (CMPB), Göttingen, Germany

Publisher

American Chemical Society (ACS)

Subject

Inorganic Chemistry,Physical and Theoretical Chemistry

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