3-(3,4-Dihydroisoquinolin-2(1H)-ylsulfonyl)benzoic Acids: Highly Potent and Selective Inhibitors of the Type 5 17-β-Hydroxysteroid Dehydrogenase AKR1C3-Reference-Cited by-同舟云学术

3-(3,4-Dihydroisoquinolin-2(1H)-ylsulfonyl)benzoic Acids: Highly Potent and Selective Inhibitors of the Type 5 17-β-Hydroxysteroid Dehydrogenase AKR1C3

Published:2012-08-21 Issue:17 Volume:55 Page:7746-7758
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Jamieson Stephen M. F.¹,Brooke Darby G.¹,Heinrich Daniel¹,Atwell Graham J.¹,Silva Shevan¹,Hamilton Emma J.¹,Turnbull Andrew P.²,Rigoreau Laurent J. M.³,Trivier Elisabeth³,Soudy Christelle³,Samlal Sharon S.³,Owen Paul J.³,Schroeder Ewald³,Raynham Tony³,Flanagan Jack U.¹,Denny William A.¹

Affiliation:

1. Auckland Cancer Society Research Centre, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand

2. Cancer Research Technology Ltd, Birkbeck College, University of London, London, U.K.

3. Cancer Research Technology Ltd, Wolfson Institute for Biomedical Research, The Cruciform Building, Gower Street, London WC1E 6BT, U.K.

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm3007867

Reference40 articles.

1. The Aldo-Keto Reductase Superfamily and its Role in Drug Metabolism and Detoxification