Novel Derivatives of Pyridylbenzo[b]thiophene-2-carboxamides and Benzo[b]thieno[2,3-c]naphthyridin-2-ones: Minor Structural Variations Provoke Major Differences of Antitumor Action Mechanisms-Reference-Cited by-同舟云学术

Novel Derivatives of Pyridylbenzo[b]thiophene-2-carboxamides and Benzo[b]thieno[2,3-c]naphthyridin-2-ones: Minor Structural Variations Provoke Major Differences of Antitumor Action Mechanisms

Published:2009-03-30 Issue:8 Volume:52 Page:2482-2492
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Ester Katja¹,Hranjec Marijana¹,Piantanida Ivo¹,Ćaleta Irena¹,Jarak Ivana¹,Pavelić Krešimir¹,Kralj Marijeta¹,Karminski-Zamola Grace¹

Affiliation:

1. Division of Molecular Medicine, “Ruđer Bošković” Institute, Bijenička Cesta 54, P.O. Box 180, HR-10000 Zagreb, Croatia, Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Marulićev trg 20, P.O. Box 177, HR-10000 Zagreb, Croatia, and Division of Organic Chemistry and Biochemistry, “Ruđer Bošković” Institute, P.O. Box 180, HR-10002 Zagreb, Croatia

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm801573v

Reference42 articles.

1. Isoindolo[2,1-a]quinoxaline Derivatives, Novel Potent Antitumor Agents with Dual Inhibition of Tubulin Polymerization and Topoisomerase I

2. Microtubule dynamics: taking aim at a moving target

3. Structural Simplification of Bioactive Natural Products with Multicomponent Synthesis. 2. Antiproliferative and Antitubulin Activities of Pyrano[3,2-c]pyridones and Pyrano[3,2-c]quinolones

4. Synthesis and Antibacterial Activity of New N-[2-(Thiophen-3-yl)ethyl] Piperazinyl Quinolones

5. CHM-1, a novel synthetic quinolone with potent and selective antimitotic antitumor activity against human hepatocellular carcinoma in vitro and in vivo

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