Structure-Based Design, Synthesis, and A-Site rRNA Cocrystal Complexes of Functionally Novel Aminoglycoside Antibiotics: C2‘ ‘ Ether Analogues of Paromomycin-Reference-Cited by-同舟云学术

Structure-Based Design, Synthesis, and A-Site rRNA Cocrystal Complexes of Functionally Novel Aminoglycoside Antibiotics: C2‘ ‘ Ether Analogues of Paromomycin

Published:2007-04-26 Issue:10 Volume:50 Page:2352-2369
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Hanessian Stephen¹,Szychowski Janek¹,Adhikari Susanta Sekhar¹,Vasquez Guillermo¹,Kandasamy Pachamuthu¹,Swayze Eric E.¹,Migawa Michael T.¹,Ranken Ray¹,François Boris¹,Wirmer-Bartoschek Julia¹,Kondo Jiro¹,Westhof Eric¹

Affiliation:

1. Department of Chemistry, Université de Montréal, C. P. 6128, Succ. Centre-Ville, Montréal, P. Q., Canada, H3C 3J7, Isis Pharmaceuticals, 2292 Faraday Drive, Carlsbad, California 92008, and Institut de Biologie Moléculaire et Cellulaire UPR9002 CNRS, Université Louis Pasteur, 15 rue René Descartes, 67084 Strasbourg Cedex, France

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm061200%2B

Reference62 articles.

1. Walsh, C.Antibiotics: Actions, Origins, Resistance; ASM Press: Washington, DC, 2003.

2. Versatility of Aminoglycosides and Prospects for Their Future

3. Efficacy and pharmacodynamics of teicoplanin given daily during the first 3 days and then on alternate days for methicillin-resistant Staphylococcus aureus infections

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