1. The Skaggs Institute for Chemical Biology and Departments of Chemistry and Immunology, Worm Institute of Research and Medicine (WIRM), and Department of Molecular and Experimental Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, Acidophil, LLC, Suite 250, 10835 Road to the Cure, San Diego, California 92121, and Department of Experimental Oncology, Istituto Nazionale per lo Studio e la Cura dei Tumori, Via Venezian 1, 20133 Milan, Italy