A Chemically Cross-Linked Knottin Dimer Binds Integrins with Picomolar Affinity and Inhibits Tumor Cell Migration and Proliferation
Author:
Affiliation:
1. Departments of †Bioengineering and ‡Chemical Engineering, Stanford University, Stanford, California 94305, United States
Funder
Stanford University
National Cancer Institute
Publisher
American Chemical Society (ACS)
Subject
Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis
Link
https://pubs.acs.org/doi/pdf/10.1021/ja508416e
Reference47 articles.
1. Integrins: Versatility, modulation, and signaling in cell adhesion
2. Extracellular Matrix Regulation of Metabolism and Implications for Tumorigenesis
3. Role of Integrins in Cancer: Survey of Expression Patterns
4. Requirement of Vascular Integrin α v β 3 for Angiogenesis
5. Integrins in cancer: biological implications and therapeutic opportunities
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