Synthesis of 1-Alkyl-2-(trifluoromethyl)azetidines and Their Regiospecific Ring Opening toward Diverse α-(Trifluoromethyl)Amines via Intermediate Azetidinium Salts-Reference-Cited by-同舟云学术

Synthesis of 1-Alkyl-2-(trifluoromethyl)azetidines and Their Regiospecific Ring Opening toward Diverse α-(Trifluoromethyl)Amines via Intermediate Azetidinium Salts

Published:2012-07-06 Issue:14 Volume:77 Page:5982-5992
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Kenis Sara¹,D’hooghe Matthias¹,Verniest Guido¹,Dang Thi Tuyet Anh²,Pham The Chinh²,Van Nguyen Tuyen²,De Kimpe Norbert¹

Affiliation:

1. Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium

2. Institute of Chemistry, Vietnam Academy of Sciences & Technology, 18 Hoang Quoc Viet, Cau giay, Hanoi, Vietnam

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jo300694y

Reference64 articles.

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2. Fluorine in medicinal chemistry: Recent therapeutic applications of fluorinated small molecules

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4. Fluorine in Pharmaceuticals: Looking Beyond Intuition

5. Organic Fluorine Hardly Ever Accepts Hydrogen Bonds

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