1. Chemistry, School of Environmental and Life Sciences, The University of Newcastle, Callaghan, NSW 2308, Australia, Department of Medical Oncology, Calvary Mater Newcastle Hospital, Waratah, NSW 2298, Australia, Cell Signalling Unit, Children’s Medical Research Institute, 214 Hawkesbury Road, Westmead, NSW 2145, Australia, Australian Institute of Marine Science, PMB 3, Townsville MC, Qld 4810, Australia, and College of Pharmacy, University of Hawaii at Hilo, Hilo-96720, Hawaii