Nonenantioselectivity Property of Human Deoxycytidine Kinase Explained by Structures of the Enzyme in Complex with l- and d-Nucleosides-Reference-Cited by-同舟云学术

Nonenantioselectivity Property of Human Deoxycytidine Kinase Explained by Structures of the Enzyme in Complex with l- and d-Nucleosides

Published:2007-05-27 Issue:13 Volume:50 Page:3004-3014
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Sabini Elisabetta¹,Hazra Saugata¹,Konrad Manfred¹,Lavie Arnon¹

Affiliation:

1. Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, 900 S. Ashland Avenue, M/C 669, Chicago, Illinois 60607, and Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, D-37077 Göttingen, Germany

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm0700215

Reference29 articles.

1. Structure and function of cellular deoxyribonucleoside kinases

2. Reaction of human UMP-CMP kinase with natural and analog substrates

3. Novel Role of 3-Phosphoglycerate Kinase, a Glycolytic Enzyme, in the Activation of L-Nucleoside Analogs, a New Class of Anticancer and Antiviral Agents

4. A comparison of the enantioselectivities of human deoxycytidine kinase and human cytidine deaminase∗

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