Structure−Activity Relationships for the Degradation Reaction of 1-β-O-Acyl Glucuronides. Part 3: Electronic and Steric Descriptors Predicting the Reactivity of Aralkyl Carboxylic Acid 1-β-O-Acyl Glucuronides-Reference-Cited by-同舟云学术

Structure−Activity Relationships for the Degradation Reaction of 1-β-O-Acyl Glucuronides. Part 3: Electronic and Steric Descriptors Predicting the Reactivity of Aralkyl Carboxylic Acid 1-β-O-Acyl Glucuronides

Published:2009-11-10 Issue:12 Volume:22 Page:1998-2008
ISSN:0893-228X
Container-title:Chemical Research in Toxicology
language:en
Short-container-title:Chem. Res. Toxicol.

Author:

Baba Akiko¹,Yoshioka Tadao¹

Affiliation:

1. Hokkaido Pharmaceutical University School of Pharmacy, 7-1 Katsuraoka-cho, Otaru, Hokkaido 047-0264, Japan

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/tx9002963

Reference75 articles.

1. A Comprehensive Listing of Bioactivation Pathways of Organic Functional Groups

2. Role of Metabolism in Drug-Induced Idiosyncratic Hepatotoxicity

3. Drug Bioactivation Covalent Binding to Target Proteins and Toxicity Relevance

4. Metabolites and Safety: What Are the Concerns, and How Should We Address Them?

5. Applying Mechanisms of Chemical Toxicity to Predict Drug Safety

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