Synthesis and Evaluation of 1,5-Disubstituted Tetrazoles as Rigid Analogues of Combretastatin A-4 with Potent Antiproliferative and Antitumor Activity-Reference-Cited by-同舟云学术

Synthesis and Evaluation of 1,5-Disubstituted Tetrazoles as Rigid Analogues of Combretastatin A-4 with Potent Antiproliferative and Antitumor Activity

Published:2011-12-21 Issue:1 Volume:55 Page:475-488
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Romagnoli Romeo¹,Baraldi Pier Giovanni¹,Salvador Maria Kimatrai¹,Preti Delia¹,Aghazadeh Tabrizi Mojgan¹,Brancale Andrea²,Fu Xian-Hua³,Li Jun³,Zhang Su-Zhan³,Hamel Ernest⁴,Bortolozzi Roberta²,Basso Giuseppe⁵,Viola Giampietro⁵

Affiliation:

1. Dipartimento di Scienze Farmaceutiche, Università di Ferrara, 44100 Ferrara, Italy

2. The Welsh School of Pharmacy, Cardiff University, King Edward VII Avenue, Cardiff, CF10 3NB, U.K.

3. Cancer Institute, Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang Province 310009, People’s Republic of China

4. Screening Technologies Branch, Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute at Frederick, National Institutes of Health, Frederick, Maryland 21702, United States

5. Laboratorio di Oncoematologia, Dipartimento di Pediatria, Università di Padova, 35131 Padova, Italy

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm2013979

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