Effects of point mutations in a hinge region on the stability, folding, and enzymic activity of Escherichia coli dihydrofolate reductase
Author:
Publisher
American Chemical Society (ACS)
Subject
Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/bi00245a020
Reference47 articles.
1. Construction of a fol mutant strain of Escherichia coli for use in dihydrofolate reductase mutagenesis experiments
2. Contributions of hydrogen bonds of Thr 157 to the thermodynamic stability of phage T4 lysozyme
3. Purification and properties of Escherichia coli dihydrofolate reductase
4. The protein data bank: A computer-based archival file for macromolecular structures
5. Crystal structures of Escherichia coli and Lactobacillus casei dihydrofolate reductase refined at 1.7 A resolution. I. General features and binding of methotrexate.
Cited by 36 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Statistical Analysis of the Role of Cavity Flexibility in Thermostability of Proteins;Polymers;2024-01-21
2. Contribution of buried distal amino acid residues in horse liver alcohol dehydrogenase to structure and catalysis;Protein Science;2018-01-25
3. Positional effects of hydrophobic non-natural amino acid mutagenesis into the surface region of murine dihydrofolate reductase on enzyme properties;Biochemical Engineering Journal;2016-05
4. Quality Matters: Extension of Clusters of Residues with Good Hydrophobic Contacts Stabilize (Hyper)Thermophilic Proteins;Journal of Chemical Information and Modeling;2014-01-28
5. Catalytic Contributions from Remote Regions of Enzyme Structure;Chemical Reviews;2011-09-19
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3