Drug-Resistant Aurora A Mutants for Cellular Target Validation of the Small Molecule Kinase Inhibitors MLN8054 and MLN8237-Reference-Cited by-同舟云学术

Drug-Resistant Aurora A Mutants for Cellular Target Validation of the Small Molecule Kinase Inhibitors MLN8054 and MLN8237

Published:2010-05-11 Issue:6 Volume:5 Page:563-576
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Sloane Dominic A.¹,Trikic Michael Z.¹,Chu Matthew L. H.²,Lamers Maria B. A. C.³,Mason Clive S.⁴,Mueller Ilka³,Savory Wendy J.⁵,Williams David H.⁶,Eyers Patrick A.¹

Affiliation:

1. Yorkshire Cancer Research Institute for Cancer Studies, School of Medicine, University of Sheffield, Sheffield S10 2RX, U.K.

2. Department of Structural Biology, Stanford University School of Medicine, Stanford, California 94305

3. Biofocus DPI, Chesterford Research Park, Chesterford Park, Saffron Walden, Essex CB10 1XL, U.K.

4. Cellexus Ltd., Hinchingbrooke Business Park, Huntingdon PE29 6PY, U.K.

5. Domainex Ltd., Cambridge Science Park, Cambridge CB4 0WG, U.K.

6. Summit PLC, Oxford OX14 4RY, U.K.

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/cb100053q

Reference51 articles.

1. Protein kinases — the major drug targets of the twenty-first century?

2. Targeting cancer with small molecule kinase inhibitors

3. Assessment of Chemical Coverage of Kinome Space and Its Implications for Kinase Drug Discovery

4. A quantitative analysis of kinase inhibitor selectivity

5. Biochemical Mechanisms of Resistance to Small-Molecule Protein Kinase Inhibitors

Cited by 101 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. A comprehensive review on role of Aurora kinase inhibitors (AKIs) in cancer therapeutics;International Journal of Biological Macromolecules;2024-04

2. Design, synthesis, and evaluation of dual EGFR/AURKB inhibitors as anticancer agents for non-small cell lung cancer;Bioorganic & Medicinal Chemistry Letters;2024-03

3. Current trends and future prospects of drug repositioning in gastrointestinal oncology;Frontiers in Pharmacology;2024-01-04

4. A drug‐resistant mutation in plant target of rapamycin validates the specificity of ATP‐competitive TOR inhibitors in vivo;The Plant Journal;2023-11-27

5. Identification and Characterization of Natural and Semisynthetic Quinones as Aurora Kinase Inhibitors;Journal of Natural Products;2022-06-10