1. Preclinical Development, GlaxoSmithKline plc., P.O. Box 1539, King of Prussia, Pennsylvania 19406, Preclinical Development, GlaxoSmithKline plc., Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, U.K., and Preclinical Development and Molecular Discovery Research, GlaxoSmithKline plc. New Frontiers Science Park, Third Avenue, Harlow, Essex CM19 5AW, U.K.