Methoxy-Substituted 3-Formyl-2-phenylindoles Inhibit Tubulin Polymerization
Author:
Affiliation:
1. Institut für Pharmazie, Universität Regensburg, D-93040 Regensburg, Germany, and Fachbereich Chemie, Fachrichtung Lebensmittelchemie und Umwelttoxikologie, Universität Kaiserslautern, D-67663 Kaiserslautern, Germany
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm980228l
Reference42 articles.
1. Interaction of Vinca Alkaloids with Tubulin: A Comparison of Vinblastine, Vincristine, and Vinorelbine
2. Activities of the Microtubule-stabilizing Agents Epothilones A and B with Purified Tubulin and in Cells Resistant to Paclitaxel (Taxol®)
3. The Microtubule-Stabilizing Agent Discodermolide Competitively Inhibits the Binding of Paclitaxel (Taxol) to Tubulin Polymers, Enhances Tubulin Nucleation Reactions More Potently than Paclitaxel, and Inhibits the Growth of Paclitaxel-Resistant Cells
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