Efficacious Cyclic N-Acyl O-Amino Phenol Duocarmycin Prodrugs
Author:
Affiliation:
1. Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, United States
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm400413r
Reference89 articles.
1. Duocarmycin SA, a new antitumor antibiotic from Streptomyces sp.
2. CC-1065(NSC 298223), a potent new antitumor agent. Improved production and isolation, characterization and antitumor activity.
3. Duocarmycin A, a new antitumor antibiotic from Streptomyces.
4. Yatakemycin, a Novel Antifungal Antibiotic Produced by Streptomyces sp. TP-A0356.
5. (+)- and ent-(-)-Duocarmycin SA and (+)- and ent-(-)-N-BOC-DSA DNA Alkylation Properties.Alkylation Site Models That Accommodate the Offset AT-Rich Adenine N3 Alkylation Selectivity of the Enantiomeric Agents
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