An Efficient Enantioselective Synthesis of the D1 Agonist (5aR,11bS)-4,5,5a,6,7,11b-Hexahydro-2-propyl-3-thia- 5-azacyclopenta[c]phenanthrene-9,10-diol (A-86929)-Reference-Cited by-同舟云学术

An Efficient Enantioselective Synthesis of the D1 Agonist (5aR,11bS)-4,5,5a,6,7,11b-Hexahydro-2-propyl-3-thia- 5-azacyclopenta[c]phenanthrene-9,10-diol (A-86929)

Published:1997-05-01 Issue:9 Volume:62 Page:2782-2785
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Ehrlich Paul P.¹,Ralston Jeffrey W.¹,Michaelides Michael R.¹

Affiliation:

1. Neuroscience Research Division, Pharmaceutical Product Discovery, Department 47C, Abbott Laboratories, 100 Abbott Park Road, Abbott Park, Illinois 60064-3500

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jo970066l

Reference6 articles.

1. (5aR,11bS)-4,5,5a,6,7,11b-Hexahydro-2-propyl-3-thia-5-azacyclopent-1-ena[c]phenanthrene-9,10-diol (A-86929): a potent and selective dopamine D1 agonist that maintain behavioral efficacy following repeated administration and characterization of its diacetyl prodrug (ABT-431)

2. L-4'-Cyano-3-(2,2,2-trifluoroacetamido)succinanilic acid and related synthetic sweetening agents

3. Olefin synthesis by reaction of stabilized carbanions with carbene equivalents. 1. Use of (iodomethyl)tributylstannane for methylenation of sulfones

4. An efficient synthesis of novel .alpha.-diketone and .alpha.-keto ester derivatives of N-protected amino acids and peptides

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