Neurosteroid Analogues. 14. Alternative Ring System Scaffolds: GABA Modulatory and Anesthetic Actions of Cyclopenta[b]phenanthrenes and Cyclopenta[b]anthracenes-Reference-Cited by-同舟云学术

Neurosteroid Analogues. 14. Alternative Ring System Scaffolds: GABA Modulatory and Anesthetic Actions of Cyclopenta[b]phenanthrenes and Cyclopenta[b]anthracenes

Published:2008-02-15 Issue:5 Volume:51 Page:1309-1318
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Scaglione Jamie B.¹,Jastrzebska Izabella¹,Krishnan Kathiresan¹,Li Ping¹,Akk Gustav¹,Manion Brad D.¹,Benz Ann¹,Taylor Amanda¹,Rath Nigam P.¹,Evers Alex S.¹,Zorumski Charles F.¹,Mennerick Steven¹,Covey Douglas F.¹

Affiliation:

1. Departments of Molecular Biology and Pharmacology, Anesthesiology, Psychiatry, Anatomy, and Neurobiology, Washington University School of Medicine, St. Louis, Missouri 63110, and Department of Chemistry and Biochemistry, University of Missouri—St. Louis, St. Louis, Missouri 63121

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm701128r

Reference41 articles.

1. Neurosteroids: Endogenous bimodal modulators of the GABAA receptor mechanism of action and physiological significance

2. Neuroactive steroids: potential therapeutic use in neurological and psychiatric disorders

3. Recent developments in structure–activity relationships for steroid modulators of GABAA receptors

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