Trimethylation Enhancement using Diazomethane (TrEnDi): Rapid On-Column Quaternization of Peptide Amino Groups via Reaction with Diazomethane Significantly Enhances Sensitivity in Mass Spectrometry Analyses via a Fixed, Permanent Positive Charge
Author:
Affiliation:
1. Department of Chemistry, Carleton University, Ottawa, Ontario K1S 5B6, Canada
2. Institute of Biochemistry, Carleton University, Ottawa, Ontario K1S 5B6, Canada
Publisher
American Chemical Society (ACS)
Subject
Analytical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/ac403349c
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