Simplified Analogues of Immucillin-G Retain Potent Human Purine Nucleoside Phosphorylase Inhibitory Activity-Reference-Cited by-同舟云学术

Simplified Analogues of Immucillin-G Retain Potent Human Purine Nucleoside Phosphorylase Inhibitory Activity

Published:2006-08-31 Issue:20 Volume:49 Page:6037-6045
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Semeraro Teresa¹,Lossani Andrea¹,Botta Maurizio¹,Ghiron Chiara¹,Alvarez Reinaldo¹,Manetti Fabrizio¹,Mugnaini Claudia¹,Valensin Silvia¹,Focher Federico¹,Corelli Federico¹

Affiliation:

1. Dipartimento Farmaco Chimico Tecnologico, Università degli Studi di Siena, Via A. De Gasperi 2, 53100 Siena, Italy, Istituto di Genetica Molecolare, CNR, Via Abbiategrasso 207, 27100 Pavia, Italy, and Sienabiotech S.p.A., Via Fiorentina 1, 53100 Siena, Italy

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm060547%2B

Reference33 articles.

1. Purine nucleoside phosphorylases: properties, functions, and clinical aspects

2. DESOXYRIBOSE-1-PHOSPHATE

3. Immucillin H, a powerful transition-state analog inhibitor of purine nucleoside phosphorylase, selectively inhibits human T lymphocytes

4. Application of crystallographic and modeling methods in the design of purine nucleoside phosphorylase inhibitors.

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