Cholesterol Allosterically Modulates the Structure and Dynamics of the Taurocholate Export Pump (ABCB11)-Reference-Cited by-同舟云学术

Cholesterol Allosterically Modulates the Structure and Dynamics of the Taurocholate Export Pump (ABCB11)

Published:2024-07-26 Issue:31 Volume:15 Page:7901-7908
ISSN:1948-7185
Container-title:The Journal of Physical Chemistry Letters
language:en
Short-container-title:J. Phys. Chem. Lett.

Author:

Hosamani Soundharya¹^ORCID,Chakraborty Sandipan¹^ORCID

Affiliation:

1. Center for Innovation in Molecular and Pharmaceutical Sciences (CIMPS), Dr. Reddy’s Institute of Life Sciences, University of Hyderabad Campus, Gachibowli, Hyderabad 500046, India

Funder

Indian Council of Medical Research

University Grants Commission

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jpclett.4c01341

Reference37 articles.

1. Lai, Y. The Bile Salt Export Pump (BSEP/ABCB11); Woodhead Publishing Series in Biomedicine; Lai, Y., Ed. Woodhead Publishing: 2013; pp 327–352.

2. Molecular Mechanism of Taurocholate Transport by the Bile Salt Export Pump, an ABC Transporter Associated with Intrahepatic Cholestasis

3. Structures of human bile acid exporter ABCB11 reveal a transport mechanism facilitated by two tandem substrate-binding pockets

4. Severe bile salt export pump (BSEP) deficiency: mutations, immunohistochemically assessed BSEP expression, and malignancy risk

5. Benign recurrent intrahepatic cholestasis type 2 is caused by mutations in ABCB11

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