Kobophenol A Inhibits Binding of Host ACE2 Receptor with Spike RBD Domain of SARS-CoV-2, a Lead Compound for Blocking COVID-19

Author:

Gangadevi Suresh1,Badavath Vishnu Nayak2ORCID,Thakur Abhishek3,Yin Na1,De Jonghe Steven4ORCID,Acevedo Orlando3ORCID,Jochmans Dirk4,Leyssen Pieter4,Wang Ke5,Neyts Johan4,Yujie Tao6,Blum Galia2ORCID

Affiliation:

1. Anhui Provincial Engineering Laboratory of Silicon-Based Materials, Bengbu University, Caoshan Road 1866, Bengbu, Anhui 233030, PR China

2. Institute for Drug Research, The Hebrew University, Jerusalem 9112001, Israel

3. Department of Chemistry, University of Miami, Coral Gables, Florida 33146, United States

4. Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, KU Leuven, Herestraat 49, 3000 Leuven, Belgium

5. College of Material and Chemical Engineering, Bengbu University, Bengbu 233030, China

6. East China University of Political Science and Law, Shanghai 20042 China

Funder

Hebrew University of Jerusalem

Anhui Provincial Engineering Laboratory of Silicon-Based Materials, Bengbu University

Publisher

American Chemical Society (ACS)

Subject

General Materials Science,Physical and Theoretical Chemistry

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