Entropy Tug-of-War Determines Solvent Effects in the Liquid–Liquid Phase Separation of a Globular Protein-Reference-Cited by-同舟云学术

Entropy Tug-of-War Determines Solvent Effects in the Liquid–Liquid Phase Separation of a Globular Protein

Published:2024-04-05 Issue:15 Volume:15 Page:4047-4055
ISSN:1948-7185
Container-title:The Journal of Physical Chemistry Letters
language:en
Short-container-title:J. Phys. Chem. Lett.

Author:

Mukherjee Saumyak¹^ORCID,Ramos Sashary²^ORCID,Pezzotti Simone²^ORCID,Kalarikkal Abhishek³,Prass Tobias M.¹^ORCID,Galazzo Laura³,Gendreizig Dominik⁴,Barbosa Natercia⁴,Bordignon Enrica³⁴^ORCID,Havenith Martina²^ORCID,Schäfer Lars V.¹^ORCID

Affiliation:

1. Center for Theoretical Chemistry, Ruhr University Bochum, D-44780 Bochum, Germany

2. Department of Physical Chemistry II, Ruhr University Bochum, D-44780 Bochum, Germany

3. Faculty of Chemistry and Biochemistry, Ruhr University Bochum, D-44780 Bochum, Germany

4. Department of Physical Chemistry, University of Geneva, Quai Ernest Ansermet 30, 1211 Geneva, Switzerland

Funder

Deutsche Forschungsgemeinschaft

H2020 Marie Sklodowska-Curie Actions

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jpclett.3c03421

Reference64 articles.

1. Biological phase separation: cell biology meets biophysics

2. Germline P Granules Are Liquid Droplets That Localize by Controlled Dissolution/Condensation

3. Biomolecular condensates: organizers of cellular biochemistry

4. Liquid–Liquid Phase Separation in Disease

5. A conceptual framework for understanding phase separation and addressing open questions and challenges

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