Synthesis of Sulfaphenazole Derivatives and Their Use as Inhibitors and Tools for Comparing the Active Sites of Human Liver Cytochromes P450 of the 2C Subfamily-Reference-Cited by-同舟云学术

Synthesis of Sulfaphenazole Derivatives and Their Use as Inhibitors and Tools for Comparing the Active Sites of Human Liver Cytochromes P450 of the 2C Subfamily

Published:2001-09-08 Issue:22 Volume:44 Page:3622-3631
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Ha-Duong Nguyêt-Thanh¹,Dijols Sylvie¹,Marques-Soares Cristina¹,Minoletti Claire¹,Dansette Patrick M.¹,Mansuy Daniel¹

Affiliation:

1. Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques, UMR 8601 CNRS, Université Paris V, 45, rue des Saints Pères, 75270 Paris Cedex 06, France

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm010861y

Reference37 articles.

1. Cytochromes P450: Their Active-Site Structure and Mechanism of Oxidation

2. Biochemistry and molecular biology of the human CYP2C subfamily

3. Diclofenac and Its Derivatives As Tools for Studying Human Cytochromes P450 Active Sites: Particular Efficiency and Regioselectivity of P450 2Cs

4. Human-liver cytochromes P-450 expressed in yeast as tools for reactive-metabolite formation studies. Oxidative activation of tienilic acid by cytochromes P-450 2C9 and 2C10

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