Dual Structure–Activity Relationship of Osteoclastogenesis Inhibitor Methyl Gerfelin Based on TEG Scanning
Author:
Affiliation:
1. Graduate School of Pharmaceutical Sciences, Tohoku University, 6-3 Aza-aoba, Aramaki, Aoba-ku, Sendai 980-8578, Japan
2. Chemical Biology Core Facility, RIKEN Advanced Science Institute, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Pharmaceutical Science,Pharmacology,Biomedical Engineering,Bioengineering,Biotechnology
Link
https://pubs.acs.org/doi/pdf/10.1021/bc3003666
Reference22 articles.
1. Osteoclast-targeting small molecules for the treatment of neoplastic bone metastases
2. Small molecules for bone diseases
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4. Gerfelin, a Novel Inhibitor of Geranylgeranyl Diphosphate Synthase from Beauveria felina QN22047: II. Structural Elucidation
5. The identification of an osteoclastogenesis inhibitor through the inhibition of glyoxalase I
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