Efficient Delivery of Sticky siRNA and Potent Gene Silencing in a Prostate Cancer Model Using a Generation 5 Triethanolamine-Core PAMAM Dendrimer-Reference-Cited by-同舟云学术

Efficient Delivery of Sticky siRNA and Potent Gene Silencing in a Prostate Cancer Model Using a Generation 5 Triethanolamine-Core PAMAM Dendrimer

Published:2012-01-20 Issue:3 Volume:9 Page:470-481
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Liu Xiaoxuan¹²³,Liu Cheng²,Laurini Erik⁴,Posocco Paola⁴,Pricl Sabrina⁴,Qu Fanqi²,Rocchi Palma³,Peng Ling¹

Affiliation:

1. Département de Chimie, Centre Interdisciplinaire de Nanoscience de Marseille, CNRS UMR 7325, Aix-Marseille Université, 163 avenue de Luminy, 13288 Marseille, France

2. State Key Laboratory of Virology, College of Chemistry and Molecular Sciences, Wuhan University, Wuhan, 430072, P. R. China

3. Centre de Recherche en Cancérologie de Marseille, UMR1068 Inserm, Institut Paoli-Calmettes, Aix-Marseille Université, France

4. Molecular Simulation Engineering (MOSE) Laboratory, Department of Industrial Engineering and Information Technology (DI3), University of Trieste, Via Valerio 10, 34127 Trieste, Italy

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/mp2006104

Reference30 articles.

1. Interfering with disease: a progress report on siRNA-based therapeutics

2. The promises and pitfalls of RNA-interference-based therapeutics

3. Current prospects for RNA interference-based therapies

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5. Polycationic dendrimers interact with RNA molecules: polyamine dendrimers inhibit the catalytic activity of Candida ribozymes

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