Acetaminophen Reactive Intermediates Target Hepatic Thioredoxin Reductase-Reference-Cited by-同舟云学术

Acetaminophen Reactive Intermediates Target Hepatic Thioredoxin Reductase

Published:2014-04-04 Issue:5 Volume:27 Page:882-894
ISSN:0893-228X
Container-title:Chemical Research in Toxicology
language:en
Short-container-title:Chem. Res. Toxicol.

Author:

Jan Yi-Hua¹,Heck Diane E.²,Dragomir Ana-Cristina³,Gardner Carol R.³,Laskin Debra L.³,Laskin Jeffrey D.¹

Affiliation:

1. Department of Environmental and Occupational Medicine, Rutgers University-Robert Wood Johnson Medical School, Piscataway, New Jersey 08854, United States

2. Department of Environmental Health Science, New York Medical College, Valhalla, New York 10595, United States

3. Department of Pharmacology and Toxicology, Rutgers University, Piscataway, New Jersey 08854, United States

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/tx5000443

Reference74 articles.

1. ACETAMINOPHEN-INDUCED HEPATOTOXICITY

2. Mechanisms of Acetaminophen-Induced Liver Necrosis

3. N-acetyl-p-benzoquinone imine: a cytochrome P-450-mediated oxidation product of acetaminophen.

4. Acetaminophen bioactivation by human cytochrome P450 enzymes and animal microsomes

5. The covalent binding of acetaminophen to protein. Evidence for cysteine residues as major sites of arylation in vitro

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