Combining In Vivo Data with In Silico Predictions for Modeling Hepatic Steatosis by Using Stratified Bagging and Conformal Prediction-Reference-Cited by-同舟云学术

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Combining In Vivo Data with In Silico Predictions for Modeling Hepatic Steatosis by Using Stratified Bagging and Conformal Prediction

Published:2020-12-21 Issue:2 Volume:34 Page:656-668
ISSN:0893-228X
Container-title:Chemical Research in Toxicology
language:en
Short-container-title:Chem. Res. Toxicol.

Author:

Jain Sankalp¹^ORCID,Norinder Ulf²,Escher Sylvia E.³,Zdrazil Barbara¹^ORCID

Affiliation:

1. Department of Pharmaceutical Chemistry, Division of Drug Design and Medicinal Chemistry, University of Vienna, 1090 Vienna, Austria

2. Unit of Toxicology Sciences, Swetox, Karolinska Institutet, SE-15136 Södertälje, Sweden

3. Fraunhofer Institute for Toxicology and Experimental Medicine (ITEM), 30625 Hannover, Germany

Funder

Austrian Science Fund

H2020 Research Infrastructures

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Link

http://pubs.acs.org/doi/pdf/10.1021/acs.chemrestox.0c00511

Reference53 articles.

1. Identification of Environmental Chemicals Associated with the Development of Toxicant-associated Fatty Liver Disease in Rodents

2. Role of nonalcoholic fatty liver disease as risk factor for drug-induced hepatotoxicity

3. Review article: drug-induced liver injury in the context of nonalcoholic fatty liver disease - a physiopathological and clinical integrated view

4. Recent Insights into the Pathogenesis of Nonalcoholic Fatty Liver Disease

5. Drug-Induced Steatohepatitis

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