Novel o-Toluidine Metabolite in Rat Urine Associated with Urinary Bladder Carcinogenesis-Reference-Cited by-同舟云学术

Novel o-Toluidine Metabolite in Rat Urine Associated with Urinary Bladder Carcinogenesis

Published:2020-04-28 Issue:7 Volume:33 Page:1907-1914
ISSN:0893-228X
Container-title:Chemical Research in Toxicology
language:en
Short-container-title:Chem. Res. Toxicol.

Author:

Tajima Yuya¹,Toyoda Takeshi²,Hirayama Yuichiro¹,Matsushita Kohei²,Yamada Takanori²,Ogawa Kumiko²,Watanabe Kenji¹^ORCID,Takamura-Enya Takeji³,Totsuka Yukari⁴^ORCID,Wakabayashi Keiji¹,Miyoshi Noriyuki¹^ORCID

Affiliation:

1. Graduate School of Integrated Pharmaceutical and Nutritional Sciences, University of Shizuoka, Shizuoka 422-8526, Japan

2. Division of Pathology, National Institute of Health Sciences, Kawasaki City, Kanagawa 210-9501, Japan

3. Department of Chemistry, Kanagawa Institute of Technology, Atsugi, Kanagawa 243-0292, Japan

4. Division of Carcinogenesis and Cancer Prevention, National Cancer Center Research Institute, Tokyo 104-0045, Japan

Funder

Ministry of Health, Labour and Welfare

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.chemrestox.0c00098

Reference18 articles.

1. Report on Carcinogens Monograph on Ortho-Toluidine; 14th Report on Carcinogens; U.S. Department of Health and Human Services: 2016.

2. An epidemic of bladder cancer: ten cases of bladder cancer in male Japanese workers exposed to ortho ‐toluidine

3. DNA adducts of ortho-toluidine in human bladder

4. DNA Double-stranded Breaks Induce Histone H2AX Phosphorylation on Serine 139

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