Replication of the Aristolochic Acid I Adenine Adduct (ALI-N6-A) by a Model Translesion Synthesis DNA Polymerase: Structural Insights on the Induction of Transversion Mutations from Molecular Dynamics Simulations

Author:

Kathuria Preetleen1ORCID,Singh Prebhleen1,Sharma Purshotam1ORCID,Wetmore Stacey D.2ORCID

Affiliation:

1. Computational Biochemistry Laboratory, Department of Chemistry and Centre for Advanced Studies in Chemistry, Panjab University, Chandigarh 160014, India

2. Department of Chemistry and Biochemistry, University of Lethbridge, Lethbridge, Alberta T1K 3M4, Canada

Funder

University Grants Commission

Canada Foundation for Innovation

University of Lethbridge

Department of Science and Technology, Ministry of Science and Technology

Natural Sciences and Engineering Research Council of Canada

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

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