New Perspectives on Drug-Induced Liver Injury Risk Assessment of Acyl Glucuronides-Reference-Cited by-同舟云学术

New Perspectives on Drug-Induced Liver Injury Risk Assessment of Acyl Glucuronides

Published:2020-06-11 Issue:7 Volume:33 Page:1551-1560
ISSN:0893-228X
Container-title:Chemical Research in Toxicology
language:en
Short-container-title:Chem. Res. Toxicol.

Author:

Walles Markus¹^ORCID,Brown Alan P.²,Zimmerlin Alfred¹,End Peter¹

Affiliation:

1. PK Sciences, Novartis Institutes for Biomedical Research, Novartis Campus, 4052 Basel, Switzerland

2. Preclinical Safety, Novartis Institutes for Biomedical Research, 220 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.chemrestox.0c00131

Reference70 articles.

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2. (2009) ICH M3 (R2) guideline on Non-Clinical Safety Studies for the Conduct of Human Clinical Trials and Marketing Authorization for Pharmaceuticals), Committee for Medicinal Use for Human Products (CHMP), European Medicine Agency, London, UK.

3. Properties of Acyl Glucuronides: Implications for Studies of the Pharmacokinetics and Metabolism of Acidic Drugs

4. Toxicity of Carboxylic Acid-Containing Drugs: The Role of Acyl Migration and CoA Conjugation Investigated

5. Mechanistic Role of Acyl Glucuronides

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