Inhibitors of 7-Dehydrocholesterol Reductase: Screening of a Collection of Pharmacologically Active Compounds in Neuro2a Cells-Reference-Cited by-同舟云学术

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Inhibitors of 7-Dehydrocholesterol Reductase: Screening of a Collection of Pharmacologically Active Compounds in Neuro2a Cells

Published:2016-04-28 Issue:5 Volume:29 Page:892-900
ISSN:0893-228X
Container-title:Chemical Research in Toxicology
language:en
Short-container-title:Chem. Res. Toxicol.

Author:

Kim Hye-Young H.¹,Korade Zeljka²,Tallman Keri A.¹,Liu Wei¹,Weaver C. David,Mirnics Karoly²,Porter Ned A.¹²

Affiliation:

1. Department of Chemistry and Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, Tennessee 37235, United States

2. Vanderbilt Kennedy Center for Research on Human Development, Vanderbilt University, Nashville, Tennessee 37235, United States

Funder

National Institute of Environmental Health Sciences

National Institute of Neurological Disorders and Stroke

National Institute of Child Health and Human Development

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.chemrestox.6b00054

Reference54 articles.

1. Biosynthesis of Cholesterol and Other Sterols

2. Oxidized derivatives of 7-dehydrocholesterol induce growth retardation in cultured rat embryos: a model for antenatal growth retardation in the Smith-Lemli-Opitz syndrome

3. Cholesterol deficit but not accumulation of aberrant sterols is the major cause of the teratogenic activity in the Smith-Lemli-Opitz syndrome animal model

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