Hierarchical Quantitative Structure–Activity Relationship Modeling Approach for Integrating Binary, Multiclass, and Regression Models of Acute Oral Systemic Toxicity-Reference-Cited by-同舟云学术

Hierarchical Quantitative Structure–Activity Relationship Modeling Approach for Integrating Binary, Multiclass, and Regression Models of Acute Oral Systemic Toxicity

Published:2020-01-24 Issue:2 Volume:33 Page:353-366
ISSN:0893-228X
Container-title:Chemical Research in Toxicology
language:en
Short-container-title:Chem. Res. Toxicol.

Author:

Li Xinhao¹,Kleinstreuer Nicole C.²³^ORCID,Fourches Denis¹^ORCID

Affiliation:

1. Department of Chemistry, Bioinformatics Research Center, North Carolina State University, Raleigh, North Carolina 27695, United States

2. Division of Intramural Research/Biostatistics and Computational Biology Branch, NIEHS, Research Triangle Park, Durham, North Carolina 27709, United States

3. National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods, NIEHS, Research Triangle Park, Durham, North Carolina 27709, United States

Funder

North Carolina State University

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.chemrestox.9b00259

Reference46 articles.

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3. Alternative approaches for acute inhalation toxicity testing to address global regulatory and non-regulatory data requirements: An international workshop report