Metabolite Profiling and Reaction Phenotyping for the in Vitro Assessment of the Bioactivation of Bromfenac
Author:
Affiliation:
1. MyoKardia, Inc., 333 Allerton Avenue, South San Francisco, California 94080, United States
Funder
MyoKardia, Inc
Publisher
American Chemical Society (ACS)
Subject
Toxicology,General Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.chemrestox.9b00268
Reference28 articles.
1. Role of Glucuronidation and P450 Oxidation in the Bioactivation of Bromfenac
2. Acute liver failure associated with prolonged use of bromfenac leading to liver transplantation
3. Bromfenac(Duract)-Associated Hepatic Failure Requiring Liver Transplantation
4. Fatal Fulminant Hepatitis Associated with Bromfenac Use
5. A systematic review of NSAIDs withdrawn from the market due to hepatotoxicity: lessons learned from the bromfenac experience
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