Modern Approaches for Asymmetric Construction of Carbon–Fluorine Quaternary Stereogenic Centers: Synthetic Challenges and Pharmaceutical Needs

Author:

Zhu Yi1,Han Jianlin1ORCID,Wang Jiandong2,Shibata Norio2ORCID,Sodeoka Mikiko3ORCID,Soloshonok Vadim A.45ORCID,Coelho Jaime A. S.6,Toste F. Dean6ORCID

Affiliation:

1. School of Chemistry and Chemical Engineering, State Key laboratory of Coordination Chemistry, Jiangsu Key Laboratory of Advanced Organic Materials, Nanjing University, 210093 Nanjing, China

2. Department of Nanopharmaceutical Sciences & Department of Frontier Materials, Nagoya Institute of Technology, Gokiso, Showa-ku, Nagoya 466-8555, Japan

3. Synthetic Organic Chemistry Laboratory, RIKEN, and RIKEN Center for Sustainable Resourse Science, 2-1 Hirosawa, Wako 351-0198, Japan

4. Department of Organic Chemistry I, Faculty of Chemistry, University of the Basque Country UPV/EHU, 20018 San Sebastian, Spain

5. IKERBASQUE, Basque Foundation for Science, 48011 Bilbao, Spain

6. Department of Chemistry, University of California, Berkeley, California 94720, United States

Funder

RIKEN

Asahi Glass Foundation

Eusko Jaurlaritza

Japan Society for the Promotion of Science

Japan Science and Technology Agency

National Natural Science Foundation of China

National Institute of General Medical Sciences

Funda??o para a Ci?ncia e a Tecnologia

Publisher

American Chemical Society (ACS)

Subject

General Chemistry

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