Amyloid Oligomers: A Joint Experimental/Computational Perspective on Alzheimer’s Disease, Parkinson’s Disease, Type II Diabetes, and Amyotrophic Lateral Sclerosis

Author:

Nguyen Phuong H.1ORCID,Ramamoorthy Ayyalusamy2ORCID,Sahoo Bikash R.2ORCID,Zheng Jie3ORCID,Faller Peter4ORCID,Straub John E.5ORCID,Dominguez Laura6ORCID,Shea Joan-Emma7ORCID,Dokholyan Nikolay V.89ORCID,De Simone Alfonso1011,Ma Buyong1213ORCID,Nussinov Ruth1214,Najafi Saeed7,Ngo Son Tung15ORCID,Loquet Antoine16ORCID,Chiricotto Mara17,Ganguly Pritam7ORCID,McCarty James18ORCID,Li Mai Suan1920ORCID,Hall Carol21ORCID,Wang Yiming21ORCID,Miller Yifat22ORCID,Melchionna Simone23,Habenstein Birgit16,Timr Stepan1,Chen Jiaxing8,Hnath Brianna8,Strodel Birgit24ORCID,Kayed Rakez25ORCID,Lesné Sylvain26,Wei Guanghong27ORCID,Sterpone Fabio1ORCID,Doig Andrew J.28ORCID,Derreumaux Philippe12930ORCID

Affiliation:

1. CNRS, UPR9080, Université de Paris, Laboratory of Theoretical Biochemistry, IBPC, Fondation Edmond de Rothschild, PSL Research University, Paris 75005, France

2. Biophysics and Department of Chemistry, University of Michigan, Ann Arbor, Michigan 48109-1055, United States

3. Department of Chemical & Biomolecular Engineering, The University of Akron, Akron, Ohio 44325, United States

4. Institut de Chimie, UMR 7177, CNRS-Université de Strasbourg, 4 rue Blaise Pascal, 67000 Strasbourg, France

5. Department of Chemistry, Boston University, 590 Commonwealth Avenue, Boston, Massachusetts 02215, United States

6. Facultad de Química, Departamento de Fisicoquímica, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico

7. Department of Chemistry and Biochemistry, and Department of Physics, University of California, Santa Barbara, California 93106, United States

8. Department of Pharmacology and Biochemistry & Molecular Biology, Penn State University College of Medicine, Hershey, Pennsylvania 17033, United States

9. Department of Chemistry, and Biomedical Engineering, Pennsylvania State University, University Park, Pennsylvania 16802, United States

10. Department of Life Sciences, Imperial College London, London SW7 2AZ, U.K.

11. Molecular Biology, University of Naples Federico II, Naples 80138, Italy

12. Basic Science Program, Leidos Biomedical Research, Inc., Cancer and Inflammation Program, National Cancer Institute, Frederick, Maryland 21702, United States

13. School of Pharmacy, Shanghai Jiao Tong University, Shanghai, China

14. Sackler Institute of Molecular Medicine, Department of Human Genetics and Molecular Medicine Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel

15. Laboratory of Theoretical and Computational Biophysics & Faculty of Applied Sciences, Ton Duc Thang University, 33000 Ho Chi Minh City, Vietnam

16. Institute of Chemistry & Biology of Membranes & Nanoobjects, (UMR5248 CBMN), CNRS, Université Bordeaux, Institut Européen de Chimie et Biologie, 33600 Pessac, France

17. Department of Chemical Engineering and Analytical Science, University of Manchester, Manchester M13 9PL, U.K.

18. Chemistry Department, Western Washington University, Bellingham, Washington 98225, United States

19. Institute for Computational Science and Technology, SBI Building, Quang Trung Software City, Tan Chanh Hiep Ward, District 12, Ho Chi Minh City 700000, Vietnam

20. Institute of Physics, Polish Academy of Sciences, Al. Lotnikow 32/46, 02-668 Warsaw, Poland

21. Department of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, North Carolina 27695-7905, United States

22. Department of Chemistry and The Ilse Katz Institute for Nanoscale Science & Technology, Ben-Gurion University of the Negev, Be’er Sheva 84105, Israel

23. ISC-CNR, via dei Taurini, 00185 Rome, Italy

24. Institute of Complex Systems: Structural Biochemistry (ICS-6), Forschungszentrum Jülich, 52425 Jülich, Germany

25. Mitchell Center for Neurodegenerative Diseases, and Departments of Neurology, Neuroscience and Cell Biology, University of Texas Medical Branch, Galveston, Texas 77555, United States

26. Department of Neuroscience, University of Minnesota, Minneapolis, Minnesota 55455, United States

27. Department of Physics, State Key Laboratory of Surface Physics, and Key Laboratory for Computational Physical Science, Multiscale Research Institute of Complex Systems, Fudan University, Shanghai 200438, China

28. Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9PT, U.K.

29. Laboratory of Theoretical Chemistry, Ton Duc Thang University, 33000 Ho Chi Minh City, Vietnam

30. Faculty of Pharmacy, Ton Duc Thang University, 33000 Ho Chi Minh City, Vietnam

Funder

Division of Chemistry

National Center for Advancing Translational Sciences

National Institute of Neurological Disorders and Stroke

Division of Molecular and Cellular Biosciences

Narodowe Centrum Nauki

National Institute on Aging

Division of Civil, Mechanical and Manufacturing Innovation

Division of Chemical, Bioengineering, Environmental, and Transport Systems

University of Minnesota

National Natural Science Foundation of China

National Institutes of Health

National Institute of General Medical Sciences

National Foundation for Science and Technology Development

Division of Materials Research

Agence Nationale de la Recherche

Israel Science Foundation

Ministry of Science and Technology of the People's Republic of China

H2020 Marie Sklodowska-Curie Actions

Consejo Nacional de Ciencia y Tecnología

Centre National de la Recherche Scientifique

FP7 Ideas: European Research Council

Helmholtz Association

H2020 European Research Council

Seventh Framework Programme

Institute of Translational Neuroscience, University of Minnesota

Passan Foundation

Department of Science and Technology, Ho Chi Minh City

Laboratorio Nacional de Cómputo de Alto Desempeño, Universidad Nacional Autónoma de México

Publisher

American Chemical Society (ACS)

Subject

General Chemistry

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