The Role of Protein Loops and Linkers in Conformational Dynamics and Allostery

Author:

Papaleo Elena12,Saladino Giorgio3,Lambrughi Matteo4,Lindorff-Larsen Kresten2,Gervasio Francesco Luigi3,Nussinov Ruth56

Affiliation:

1. Computational Biology Laboratory, Unit of Statistics, Bioinformatics and Registry, Danish Cancer Society Research Center, Strandboulevarden 49, 2100 Copenhagen, Denmark

2. Structural Biology and NMR Laboratory, Department of Biology, University of Copenhagen, 2200 Copenhagen, Denmark

3. Department of Chemistry, University College London, London WC1E 6BT, United Kingdom

4. Department of Biotechnology and Biosciences, University of Milano-Bicocca, Piazza della Scienza 2, 20126 Milan, Italy

5. Cancer and Inflammation Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, National Cancer Institute Frederick, Frederick, Maryland 21702, United States

6. Sackler Institute of Molecular Medicine, Department of Human Genetics and Molecular Medicine Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel

Funder

Engineering and Physical Sciences Research Council

National Cancer Institute

European Commission

Novo Nordisk

Det Frie Forskningsråd

Velux Fonden

Carlsbergfondet

Lundbeckfonden

Publisher

American Chemical Society (ACS)

Subject

General Chemistry

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