Urinary Metabolomics Identified Metabolic Perturbations Associated with Gutka, a Smokeless Form of Tobacco

Author:

Jorvekar Sachin B.1,Jala Aishwarya1ORCID,Rai Avdhesh2,Jangili Shraddha3,Adla Deepthi3,Borkar Gautam4,Das Anupam5,Kakati Kaberi5,Das Kishore5,Sarma Anupam6,Mutheneni Srinivasa Rao3,Borkar Roshan M.1ORCID

Affiliation:

1. Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research (NIPER), Guwahati, Changsari 781101, India

2. DBT Centre for Molecular Biology and Cancer Research, Dr. Bhubaneswar Borooah Cancer Institute, Guwahati 781016, India

3. Applied Biology Division, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad 500007, Telangana India

4. Department of Information Technology, D. Y. Patil Ramroa Adik Institute of Technology, D. Y. Patil deemed to be University, Nerul, Navi Mumbai 400706, India

5. Department of Head and Neck Oncology, Dr. Bhubaneswar Borooah Cancer Institute, Guwahati 781016, India

6. Department of Onco-Pathology, Dr. Bhubaneswar Borooah Cancer Institute, Guwahati 781016, India

Funder

Science and Engineering Research Board

Department of Pharmaceuticals, Ministry of Chemicals and Fertilizers, India

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Reference50 articles.

1. Gutka: a major new tobacco hazard in India

2. Chemistry and toxicology of smokeless tobacco

3. IARC. Smokeless Tobacco and Some Tobacco-Speicific N-Nitrosamines. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans; IARC: Lyon, France, 2007; Vol. 89, pp 223–276.

4. Alterations in the sputum proteome and transcriptome in smokers and early-stage COPD subjects

5. Tobacco Smoking Leads to Extensive Genome-Wide Changes in DNA Methylation

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