8-Oxo-2′-deoxyguanosine Replication in Mutational Hot Spot Sequences of the <i>p53</i> Gene in Human Cells Is Less Mutagenic than That of the Corresponding Formamidopyrimidine-Reference-Cited by-同舟云学术

8-Oxo-2′-deoxyguanosine Replication in Mutational Hot Spot Sequences of the p53 Gene in Human Cells Is Less Mutagenic than That of the Corresponding Formamidopyrimidine

Published:2023-04-24 Issue:5 Volume:36 Page:782-789
ISSN:0893-228X
Container-title:Chemical Research in Toxicology
language:en
Short-container-title:Chem. Res. Toxicol.

Author:

Stanio Stephen¹,Bacurio Jan Henric T.¹,Yang Haozhe²,Greenberg Marc M.²^ORCID,Basu Ashis K.¹^ORCID

Affiliation:

1. Department of Chemistry, University of Connecticut, Storrs, Connecticut 06269, United States

2. Department of Chemistry, Johns Hopkins University, Baltimore, Maryland 21218, United States

Funder

National Institute of Environmental Health Sciences

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.chemrestox.3c00069

Reference54 articles.

1. Base and Nucleotide Excision Repair of Oxidatively Generated Guanine Lesions in DNA

2. Oxidatively induced DNA damage and its repair in cancer

3. Oxidatively Generated Damage to the Guanine Moiety of DNA: Mechanistic Aspects and Formation in Cells

4. Reaction of HO. with Guanine Derivatives in Aqueous Solution: Formation of Two Different Redox-Active OH-Adduct Radicals and Their Unimolecular Transformation Reactions. Properties of G(-H).

5. The Formamidopyrimidines: Purine Lesions Formed in Competition With 8-Oxopurines From Oxidative Stress

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4. Molecular Mechanism of RNA Polymerase II Transcriptional Mutagenesis by the Epimerizable DNA Lesion, Fapy·dG;Journal of the American Chemical Society;2024-02-23

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