Development of a Fluorescent-Labeled Trapping Reagent to Detect Reactive Acyl Glucuronides-Reference-Cited by-同舟云学术

Development of a Fluorescent-Labeled Trapping Reagent to Detect Reactive Acyl Glucuronides

Published:2021-10-27 Issue:11 Volume:34 Page:2343-2352
ISSN:0893-228X
Container-title:Chemical Research in Toxicology
language:en
Short-container-title:Chem. Res. Toxicol.

Author:

Shibazaki Chikako¹,Mashita Okishi²,Takahashi Kyoko³,Nakamura Shigeo³,Mashino Tadahiko¹,Ohe Tomoyuki¹^ORCID

Affiliation:

1. Faculty of Pharmacy, Keio University, 1-5-30 Shibakoen, Minato-ku, Tokyo 105-8512, Japan

2. Laboratory for Safety Assessment and ADME, Pharmaceuticals Research Center, Asahi Kasei Pharma Corporation, 632-1 Mifuku, Izunokuni, Shizuoka 410-2321, Japan

3. Department of Chemistry, Nippon Medical School, 1-7-1 Kyonan-cho, Musashino-shi, Tokyo 180−0023, Japan

Funder

Japan Agency for Medical Research and Development

Asahi Kasei Pharma Corporation

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.chemrestox.1c00236

Reference38 articles.

1. Acyl Glucuronides Revisited: Is the Glucuronidation Proces a Toxification as Well as a Detoxification Mechanism?

2. Acyl glucuronides: the good, the bad and the ugly

3. Properties of Acyl Glucuronides: Implications for Studies of the Pharmacokinetics and Metabolism of Acidic Drugs

4. Selective acylation of methyl α-d-glucopyranoside at O-6 by reaction with hexachloroacetone and pentachloroacetone

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