Inhibition of CYP3A7 DHEA-S Oxidation by Lopinavir and Ritonavir: An Alternative Mechanism for Adrenal Impairment in HIV Antiretroviral-Treated Neonates

Author:

Kandel Sylvie E.1ORCID,Lampe Jed N.1ORCID

Affiliation:

1. Department of Pharmaceutical Sciences, Skaggs School of Pharmacy, University of Colorado, Aurora, Colorado 80045, United States

Funder

National Institute of Allergy and Infectious Diseases

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Reference58 articles.

1. Paediatric HIV-1 infection: updated strategies of prevention mother-to-child transmission

2. United Nations Children’s Fund. (2020) Elimination of mother-to-child transmission: progress in reducing new HIV infections among children, but not fast enough to save lives. Available from https://data.unicef.org/topic/hivaids/emtct/ (accessed 2021-04-01).

3. World Health Organization. (2010) Antiretroviral drugs for treating pregnant women and preventing HIV infection in infants. Recommendations for a public health approach. Available from https://www.who.int/hiv/pub/mtct/antiretroviral2010/en/ (accessed 2021-04-01).

4. World Health Organization. (2019) Update of recommendations on first- and second-line antiretroviral regimens. Available from https://www.who.int/hiv/pub/arv/arv-update-2019-policy/en/ (accessed 2021-04-01).

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