Nanoparticle Surface Functionality Dictates Cellular and Systemic Toxicity

Author:

Saei Amir Ata1,Yazdani Mahdieh2,Lohse Samuel E.3,Bakhtiary Zahra4,Serpooshan Vahid5,Ghavami Mahdi6,Asadian Mahtab7,Mashaghi Samaneh8,Dreaden Erik C.9,Mashaghi Alireza1011121314,Mahmoudi Morteza15ORCID

Affiliation:

1. Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm 171 77, Sweden

2. Department of Chemistry, University of Massachusetts Amherst, Amherst, Massachusetts 01003, United States

3. Physical and Environment Sciences Program, Colorado Mesa University, Grand Junction, Colorado 81501, United States

4. Research Center for Pharmaceutical Nanotechnology, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz 5166/15731, Iran

5. Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, California 94305, United States

6. Department of Cellular and Molecular Medicine, Faculty of Health Sciences, University of Copenhagen, Copenhagen 1165, Denmark

7. Faculty of Engineering & Architecture, Department of Applied Physics, Research Unit Plasma Technology (RUPT), Ghent University, Ghent 9000, Belgium

8. School of Engineering and Applied Sciences and Department of Physics, Harvard University, 29 Oxford Street, Cambridge, Massachusetts 02138, United States

9. Koch Institute for Integrative Cancer Research, Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States

10. Leiden Academic Centre for Drug Research, Faculty of Mathematics and Natural Sciences, Leiden University, Leiden 2311 EZ, The Netherlands

11. Massachusetts Eye & Ear Infirmary and Harvard Medical School, Boston, Massachusetts 02115, United States

12. Dana-Farber Cancer Institute, Boston, Massachusetts 02215, United States

13. Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States

14. Basir Eye Health Research Center, Tehran 1418643561, Iran

15. Department of Anesthesiology, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts 02115, United States

Publisher

American Chemical Society (ACS)

Subject

Materials Chemistry,General Chemical Engineering,General Chemistry

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