4-Hydroxy-7-oxo-5-heptenoic Acid Lactone Is a Potent Inducer of the Complement Pathway in Human Retinal Pigmented Epithelial Cells-Reference-Cited by-同舟云学术

4-Hydroxy-7-oxo-5-heptenoic Acid Lactone Is a Potent Inducer of the Complement Pathway in Human Retinal Pigmented Epithelial Cells

Published:2018-06-08 Issue:8 Volume:31 Page:666-679
ISSN:0893-228X
Container-title:Chemical Research in Toxicology
language:en
Short-container-title:Chem. Res. Toxicol.

Author:

Linetsky Mikhail¹,Bondelid Karina S.²,Losovskiy Sofiya³,Gabyak Vadym⁴,Rullo Mario J.²,Stiadle Thomas I.¹,Munjapara Vasu²,Saxena Priyali²,Ma Duoming¹,Cheng Yu-Shiuan¹^ORCID,Howes Andrew M.²,Udeigwe Emeka¹,Salomon Robert G.¹⁵^ORCID

Affiliation:

1. Department of Chemistry, Case Western Reserve University, Cleveland, Ohio 44106, United States

2. Department of Biochemistry, Case Western Reserve University, Cleveland, Ohio 44106, United States

3. Department of Chemistry, Cleveland State University, Cleveland, Ohio 44115, United States

4. Department of Biological, Geological, and Environmental Sciences, Cleveland State University, Cleveland, Ohio 44115, United States

5. Department of Ophthalmology & Visual Sciences, Case Western Reserve University, Cleveland, Ohio 44106, United States

Funder

U.S. Department of Health and Human Services

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.chemrestox.8b00028

Reference88 articles.

2. Complement Activation and Inflammatory Processes in Drusen Formation and Age Related Macular Degeneration

3. A role for local inflammation in the formation of drusen in the aging eye

4. An Integrated Hypothesis That Considers Drusen as Biomarkers of Immune-Mediated Processes at the RPE-Bruch's Membrane Interface in Aging and Age-Related Macular Degeneration

5. A Potential Role for Immune Complex Pathogenesis in Drusen Formation

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