Differential Induction of Cytoplasmic Vacuolization and Methuosis by Novel 2-Indolyl-Substituted Pyridinylpropenones-Reference-Cited by-同舟云学术

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Differential Induction of Cytoplasmic Vacuolization and Methuosis by Novel 2-Indolyl-Substituted Pyridinylpropenones

Published:2013-11-08 Issue:1 Volume:5 Page:73-77
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Trabbic Christopher J.¹,Dietsch Heather M.²,Alexander Evan M.¹,Nagy Peter I.¹,Robinson Michael W.¹²,Overmeyer Jean H.²,Maltese William A.²,Erhardt Paul W.¹

Affiliation:

1. Center for Drug Design and Development, Department of Medicinal & Biological Chemistry, University of Toledo College of Pharmacy and Pharmaceutical Sciences, 2801 West Bancroft Avenue, Toledo, Ohio 43606, United States

2. Department of Biochemistry and Cancer Biology, University of Toledo College of Medicine, 3000 Arlington Avenue, Toledo, Ohio 43614, United States

Funder

National Institutes of Health

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ml4003925

Reference17 articles.

1. DNA and its associated processes as targets for cancer therapy

2. Microtubule-binding agents: a dynamic field of cancer therapeutics

3. Pharmacological targeting of endoplasmic reticulum stress signaling in cancer

4. The Role of the Apoptotic Machinery in Tumor Suppression

5. Tumour stem cells and drug resistance

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2. Structure–activity relationship studies on iezoside, a highly potent Ca2+ ATPase inhibitor;Bulletin of the Chemical Society of Japan;2024-07

3. Design, synthesis, and antiproliferative activity of new indole/1,2,4‐triazole/chalcone hybrids as EGFR and/or c‐MET inhibitors;Archiv der Pharmazie;2024-06-21

4. Discovery of Potent and Selective Phosphatidylinositol 3-Phosphate 5-Kinase (PIKfyve) Inhibitors as Methuosis Inducers;Journal of Medicinal Chemistry;2023-12-20

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