Protein Kinase CK2 Is a Central Regulator of Topoisomerase I Hyperphosphorylation and Camptothecin Sensitivity in Cancer Cell Lines
Author:
Affiliation:
1. Torrey Pines Institute for Molecular Studies, 3550 General Atomics Court, San Diego, California 92121, United States
Publisher
American Chemical Society (ACS)
Subject
Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/bi101110e
Reference87 articles.
1. DNA Topoisomerases: Structure, Function, and Mechanism
2. Cellular roles of DNA topoisomerases: a molecular perspective
3. DNA Topoisomerase I Inhibitors: Chemistry, Biology, and Interfacial Inhibition
4. Topoisomerase I levels in the NCI-60 cancer cell line panel determined by validated ELISA and microarray analysis and correlation with indenoisoquinoline sensitivity
5. Exon Array Analyses across the NCI-60 Reveal Potential Regulation of TOP1 by Transcription Pausing at Guanosine Quartets in the First Intron
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