Positive Allosteric Modulators of 2-Amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic Acid Receptors Belonging to 4-Cyclopropyl-3,4-dihydro-2H-1,2,4-pyridothiadiazine Dioxides and Diversely Chloro-Substituted 4-Cyclopropyl-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-Dioxides

Author:

Francotte Pierre1,Nørholm Ann-Beth2,Deva Taru2,Olsen Lars2,Frydenvang Karla2,Goffin Eric1,Fraikin Pierre1,de Tullio Pascal1,Challal Sylvie3,Thomas Jean-Yves3,Iop Fabrice3,Louis Caroline3,Botez-Pop Iuliana3,Lestage Pierre3,Danober Laurence3,Kastrup Jette S.2,Pirotte Bernard1

Affiliation:

1. Department of Medicinal Chemistry, Center for Interdisciplinary Research on Medicines (CIRM), University of Liege, Avenue de l’Hôpital, 1, B36, B-4000 Liège, Belgium

2. Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken, 2, DK-2100 Copenhagen, Denmark

3. Institut de Recherches Servier, 125 Chemin de Ronde, F-78290 Croissy-sur-Seine, France

Funder

Fonds De La Recherche Scientifique - FNRS

Servier

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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