Discovery of a Novel Series of Potent and Selective Substrate-Based Inhibitors of p60c-src Protein Tyrosine Kinase: Conformational and Topographical Constraints in Peptide Design-Reference-Cited by-同舟云学术

Discovery of a Novel Series of Potent and Selective Substrate-Based Inhibitors of p60c-src Protein Tyrosine Kinase: Conformational and Topographical Constraints in Peptide Design

Published:1998-05-28 Issue:13 Volume:41 Page:2252-2260
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Alfaro-Lopez Josue¹,Yuan Wei¹,Phan Brigitte C.¹,Kamath Jayesh¹,Lou Qiang¹,Lam Kit S.¹,Hruby Victor J.¹

Affiliation:

1. Department of Chemistry, Arizona Cancer Center, and Department of Medicine, University of Arizona, Tucson, Arizona

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm9707885

Reference61 articles.

1. Crystal structure of an integrin-binding fragment of vascular cell adhesion molecule-1 at 1.8 Å resolution

2. Signalling by the p60c-src family of protein—tyrosine kinases

Cited by 61 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Activated tyrosine kinase c‐Src‐responsive artificial gene carrier: in vitro and in vivo evaluation;ChemistrySelect;2024-01-04

2. The prospect of substrate-based kinase inhibitors to improve target selectivity and overcome drug resistance;Chemical Science;2024

3. Identification and Optimization of Protein Tyrosine Phosphatase Inhibitors Via Fragment Ligation;Methods in Molecular Biology;2023-12-27

4. High-throughput profiling of sequence recognition by tyrosine kinases and SH2 domains using bacterial peptide display;eLife;2023-03-16

5. A Model of Transcriptional Activation of DNA by Loosening of Chromatin Structure;Chemistry Letters;2022-12-05